Three-year outcomes following transcatheter tricuspid valve edge-to-edge repair

Abstract Background Tricuspid regurgitation (TR) has long been neglected due to limited therapeutic options. Within the past five years, transcatheter tricuspid valve edge-to-edge repair (T-TEER) become a valuable tool in treatment of TR besides diuretic medical therapy and surgery. Owing its novelty, data on long-term survival after T-TEER for relevant are sparse. Beyond that, there is uncertainty impact reduction outcomes successful T-TEER. Purpose This study sought investigate outcome symptomatic TR. We evaluated patients with Methods Consecutive who underwent isolated from 2016 until 2022 at high-volume university center were included study. Procedural success was defined as least one degree reduction. Long-term endpoint three-year all-cause mortality. Survival follow-up completed via phone calls themselves, next kin, local practitioners using German national population registry. Post-procedural assessed by interventionalist echocardiographer end procedure. Results A total 244 period present analysis (mean age 77.7±8.7 years; 50.8% female). Patients highly represented New York Heart Association functional class ≥ III 95.9% cases. 4+ 128 (52.2%), 3+ 106 (43.4%) 2+ 10 (6.1%). The etiology predominately (88.5%), while 5.4% presented degenerative 6.1% mixed etiology. Median time last contact or death 365 days (interquartile range 166–809 days). Three-year available 98% eligible patients. performed mean number 2.0±0.6 devices (Mitra-/TriClip 53%; PASCAL 47%). 1+ 126 (51.6%), 101 (41.4%) 17 (7.0%). rates one, two three years 76%, 68% 56%. Among procedural (at 1° reduction), higher post-procedural associated trend towards reduced postinterventional (Figure 1). absolute did not 2). Conclusion effectively reduces severity shows high success. While extent yield prognostic value terms survival, showed regarding outcome. These results indicate that techniques strategies should be refined achieve TR1+ Funding Acknowledgement Type funding sources: None.